aIdentity to full-length predicted protein. The predicted BapR protein sequence from B. cenocepacia H111 was used to search against the Burkholderia Genome Database (www.burkholderia.com) with the TBL
Table S3. Driver gene analysis by MutSig. The two genes with q value <â10â3 (TP53 and FANCC, highlighted in yellow) were considered significantly mutated. (XLSX 10 kb)
Few relevant studies have been done to address the frequency of germline mutations in Familial Egyptian BC patients and it was only to investigate BRCA1/2 germline profiling. Thus, it was important to
Wildtype and mutant strains generated during the course of this study are listed with specific mutations that were introduced. Strains utilized in this study.