Phosphoinositide 3-Kinase gamma bound to a thiazole inhibitor
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Phosphoinositide 3-Kinase gamma bound to a thiazole inhibitor Descriptor: N-[2-(3,3-dimethylbutoxy)ethyl]-N'-{4-methyl-5-[(pyridin-4-yl)ethynyl]-1,3-thiazol-2-yl}urea, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Authors: Jacobs, M.D, Griffith, J.P. Deposit date: 2020-10-27 Release date: 2021-03-24 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Discovery of a Novel Series of Potent and Selective Alkynylthiazole-Derived PI3K gamma Inhibitors. Acs Med.Chem.Lett., 12, 2021
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2020-10-27
