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Crystal structure of human MMP-2 catalytic domain in complex with inhibitor

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Protein Data Bank Japan2023-11-15 更新2026-04-25 收录
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Crystal structure of human MMP-2 catalytic domain in complex with inhibitor Descriptor: CALCIUM ION, GZS-ASN-ASP-ALA-LEU-IML-EOE-NH2, Matrix metalloproteinase-2, ... Authors: Kamitani, M, Mima, M, Takeuchi, T. Deposit date: 2022-04-05 Release date: 2022-06-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery of Aryloxyphenyl-Heptapeptide Hybrids as Potent and Selective Matrix Metalloproteinase-2 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis. J.Med.Chem., 65, 2022
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2022-04-05
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