Asymmetric nucleosomes flank promoters in the budding yeast genome

Alliance of Genome Resources2026-08-01 收录

核小体结构不对称性

染色质动态

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Nucleosomes in active chromatin are dynamic, but whether they have distinct structural conformations is unknown

Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair

DNA复制

染色质动态

Constitutive heterochromatin is considered as a functionally inert genome compartment, important for its architecture and stability. How such stable structure is maintained is not well understood. Her

DataCite Commons2020-08-26 更新80

CRISPR-mediated multiplexed live cell imaging of nonrepetitive genomic loci with one guide RNA per locus (Imaging Data)

基因成像

染色质动态

Three-dimensional (3D) structures of the genome are dynamic, heterogeneous and functionally important. Live cell imaging has become the leading method for chromatin dynamics tracking. However, existin

DataCite Commons2022-03-07 更新50

Chromatin Dynamics during DNA Replication

染色质动态

组蛋白修饰

The epigenetic landscape is shaped by both gene transcription and DNA replication. To distinguish contributions of these processes, we followed the cell cycle dynamics of ten histone modifications. T

NIAID Data Ecosystem30

High resolution chromatin dynamics during a yeast stress response

染色质动态

组蛋白修饰

Covalent histone modifications are highly conserved and play multiple roles in eukaryotic transcription regulation. Because of extensive crosstalk between transcriptional processes and histone modific

NIAID Data Ecosystem70

Chromatin states and genomic organization impact local replication features and timing [ChIP-seq]

基因组调控

染色质动态

Replication timing (RT) control is linked to histone modifications (HMs) and genome architecture. However, HM landscape across cell cycle and its relationship with RT and chromatin modifiers have not

NIAID Data Ecosystem40

Asymmetric nucleosomes flank promoters in the budding yeast genome

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