MAGeCK gene summary files

NIAID Data Ecosystem2026-03-13 收录

CRISPRi筛选

药物靶点发现

数据链接：

https://figshare.com/articles/dataset/MAGeCK_gene_summary_files/16526631 数据链接链接失效反馈

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资源简介：

MAGeck gene summary files for cancer cells - dmso vs drug treatment - CRISPR/Cas9 vs CRISPR activation screens

创建时间：

2022-06-23

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Genes we prioritised as drug targets that had MR and colocalization evidence with other indications.

药物靶点发现

基因-疾病关联

Gene expression-disease relationship identified in the main MR (instrument-gene-indication): Alzheimer’s disease (AD), Schizophrenia (Sz), anorexia (AN), suggested direction of drug action according t

Figshare2021-01-08 更新00

RNA-sequencing and CRISPR/Cas9 Screen of PEO1 cells grown in suspension.

CRISPRi筛选

失巢凋亡逃逸

RNA-sequencing of PEO1 cells grown in suspension (SUS1 and SUS3) was performed to evaluate transcriptional reprogramming during anokis escape. CRISPR/Cas9 screen of PEO1 cells grown in adherent and su

NIAID Data Ecosystem00

Crystal structure of the PIN1 and fragment 35 complex.

蛋白质晶体学

药物靶点发现

Crystal structure of the PIN1 and fragment 35 complex. Descriptor: (1-methylindazol-3-yl)methanol, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

Protein Data Bank Japan2025-10-15 更新00

PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal Apo12 (dataset 1) from the KIT library screening campaign, data used for ground state calculation

SARS-CoV-2Nsp1结构分析

药物靶点发现

PanDDA analysis group deposition -- SARS-CoV-2 Nsp1 crystal Apo12 (dataset 1) from the KIT library screening campaign, data used for ground state calculation

NIAID Data Ecosystem00

MAGeCK gene summary files

资源简介：

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