five

Time-course whole brain transcriptome and methylome profiles of early life high GC exposed zebrafish

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP138527
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Whole-brain transcriptome (mRNA) profiles of zebrafish which exposed to elavated glucocorticoid (GC) optogenetically at 6, 13, 120 day-post-fertilization (dpf), and post-predatory stress (looming dots stress) at 120 dpf. All subjective adults (at 120 dpf) were female. Tubingen strain was used as wildtype control and brains from transgenic line Tg(star:bPAC-2A-tdTomato)uoe300 +/- and -/- were sequenced on Illumina NovaSeq6000 by TRON gGmbH (Mainz, Germany). Paired-end TruSeq Stranded mRNA libraries (Illumina, CA, USA) were constructed, and over 20M of 50 bp reads/sample were sequenced. Oxford Nanopore sequencing was used for DNA methylation identification. These data were generated for the study by Choi et al. 2024. https://www.biorxiv.org/content/10.1101/2023.02.13.528363v4
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2024-02-09
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