The U1 antisense morpholino oligonucleotide (AMO) disrupts U1 snRNP structure to promote intronic PCPA modification of pre-mRNAs

NIAID Data Ecosystem2026-05-01 收录

可变多聚腺苷酸化

U1snRNP功能

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE192943 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-05-25

Additional file 2: of QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data

可变多聚腺苷酸化

神经细胞转录组

Neuronal differentiation APA. This tab-delimited file contains the QAPA-estimated PAU and Sailfish TPM values of each 3â˛ UTR isoform for samples from the Hubbard et al. [29] RNA-seq dataset. (TXT 62

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Additional file 10: of Alternative polyadenylation produces multiple 3’ untranslated regions of odorant receptor mRNAs in mouse olfactory sensory neurons

可变多聚腺苷酸化

嗅觉受体基因

Table S4. Alternative 3′ ends for pilot genes annotated from RNA-Seq data and RL-PAT experimental validation. The 3′ end positions and the relative abundances of the resulting 3’UTR isoforms were obta

Figshare2019-07-13 更新30

ChIP-seq analysis for core 3' processing factors in control and U1 AMO-treated HeLa cells. ChIP-seq analysis for core 3' processing factors in control and U1 AMO-treated HeLa cells

"RNA3末端加工"

U1snRNP功能

To understand the effect of U1 AMO treatment on chromatin binding profiles of core 3' processing factors, we carried out ChIP-seq analysis for several core 3' processing factors after control and U1 A

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The 3' end processing factor PCF11 regulates gene expression based on gene size and intronic polyadenylation. The 3' end processing factor PCF11 regulates gene expression based on gene size and intronic polyadenylation

基因表达调控

可变多聚腺苷酸化

Genes with different sizes have distinct expression patterns and functions. Here we show that the 3' end processing PCF11 modulates gene expression according to gene size. Gene density and polyA site

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Additional file 5 of Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation

可变多聚腺苷酸化

生物信息学基准

Additional file 5: DaPars2.PAS.sites. DaPars2 PAS sites with PAU > 5% (BED format).

Figshare2021-10-15 更新30