Lysosomal Protein Transmembrane 5 Promotes Lung-Specific Metastasis by Regulating BMPR1A Lysosomal Degradation
收藏NIAID Data Ecosystem2026-03-12 收录
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Organotropism during cancer metastasis occurs frequently and the mechanism remains poorly understood. Organ-specific metastatic derivatives of renal cancer were generated by repeated intracardiac inoculation and metastases clone selection/expansion, using a luciferase-labeled murine renal cancer cell line Renca. After that, genome-wide transcriptional profiling was performed to identify molecules associated with different metastatic phenotypes.
创建时间：
2021-04-24
