Lactate Dehydrogenase A in complex with a substituted pyrazine inhibitor compound 18

Lactate Dehydrogenase A in complex with a substituted pyrazine inhibitor compound 18 Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-(5-amino-6-{[(1R)-1-phenylethyl]amino}pyrazin-2-yl)-4-chlorobenzoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Eigenbrot, C, Ultsch, M. Deposit date: 2013-08-06 Release date: 2013-09-04 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.052 Å) Cite: Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 23, 2013