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Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound Descriptor: Cathepsin K, N-[(1S)-1-({[(3S,4S,7R)-3-HYDROXY-7-METHYL-1-(PYRIDIN-2-YLSULFONYL)-2,3,4,7-TETRAHYDRO-1H-AZEPIN-4-YL]AMINO}CARBONYL)-3-METHYLBUTYL]-1-BENZOFURAN-2-CARBOXAMIDE Authors: Yamashita, D.S, Baoguang, Z. Deposit date: 2006-01-24 Release date: 2007-01-30 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors. J.Med.Chem., 49, 2006
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2006-01-24
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