Response of Streptococcus mutans wild type and lrgAB-deficient strains to environemntal stressors encountered in the oral cavity

We assesed the transcriptional response of wild-type and isogenic lrgAB mutant to growth in the presence of three different stress conditions (aerobiosis, high-temperature, and the cell-wall active antibiotic vancomycin) by using RNA-seq Overall design: Examination of mRNA levels at the mid-exponential phase of growth, in triplicates