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Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate.

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3fh7
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Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate. Descriptor: 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate, ACETATE ION, GLYCEROL, ... Authors: Mamat, B, Davies, D.R. Deposit date: 2008-12-08 Release date: 2010-01-05 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis. J.Med.Chem., 53, 2010
创建时间:
2008-12-08
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