A heatmap of the normalized signal to noise (S/N) ratios used to identify the anti-LAM Ig pairs most strongly reactive to purified cLAM purified from five different lineages of MTB and the pooled data from all lineages.

All data points highlighted in deepening shades of blue are ≥90% of the output from the reference assay pair (RAP). Capture Igs are in the vertical column and detector ones in the horizontal row. Unfilled boxes represent samples with a S/N output of ≤89% as compared to the RAP. Key: MTB, Mycobacterium tuberculosis; L, Lineage; RAP, Reference Assay Pair (S4-20/A194-01).