Crystal Structure of EGFR(L858R/T790M/C797S) in complex with CH7233163
收藏Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal Structure of EGFR(L858R/T790M/C797S) in complex with CH7233163 Descriptor: Epidermal growth factor receptor, N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine Authors: Kawauchi, H, Fukami, T.A, Sato, S, Endo, M, Torizawa, T, Kashima, K, Chiba, T, Sakamoto, H. Deposit date: 2020-01-27 Release date: 2020-10-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.315 Å) Cite: CH7233163 Overcomes Osimertinib-Resistant EGFR-Del19/T790M/C797S Mutation. Mol.Cancer Ther., 19, 2020
创建时间：
2020-01-27
