List of 22 Target genes up-regulated following UPF1 silencing in HCT116 and their mutational status.

The threshold for re-expression was considered significant when the fold change was >1.5 (see the Materials and Methods section). Newly described target genes for instability in MSI CRCs are indicated in bold characters. Hmz: homozygously mutated at the coding repeat tract in HCT116. Htz: heterozygously mutated at the coding repeat tract in HCT116. wt: not mutated at the coding repeat tract in HCT116. Target genes that have been already described to be mutated in MSI CRCs are indicated with an *.