MOESM1 of Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

Additional file 1: Table S1. Provides general sequencing statistics. Tables S2 and S3. Contain a catalogue of all detected SNVs and indels, respectively. Table S4. Contains a summary of all detected genetic alterations. Table S5. Provides the numerical values of de novo SNV signatures. Table S6. Contains numerical data for cosine similarity and Pearson correlation values between SNV signatures. Table S7. Lists all detected and post-filtered SVs. Table S8. Provides all measured IC50 doses on all cell lines. Table S9. Lists the sources of all chemotherapeutic drugs used in this study. Table S10. Provides the identifier, genotype, mutation data and SNV signature contributions of analysed TCGA samples. Table S11. Contains a catalogue of all detected coding SNVs in the ancestral clones. Table S12. Contains aggregated indel profiles according to PCAWG nomenclature.