Quant-seq analysis of differential polyadenylation site usages in caused by different Pol II mutants with slow elongation rates in Flp-In-293 cells and dual inhibition of CDK12 and CDK13 by THZ531 HEK293T cells
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下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP234557
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资源简介:
We used 3' RNA-Seq to determine the effects of slow elongating Pol II on polyadenatltion site usages, also the effects of CDK12 and CDK13 inhibition caused by THZ531 on alternative polyadenylation Overall design: We performed 3'RNA-seq (Quantseq) on Flp-In-293 cells with slow elongating or wild-type a-amanitin resistant Pol II, as well as THZ531/DMSO treated HEK293T cells to compare the the effect of slow elongating Pol II to CDK12 and CDK13 inhibtion.
创建时间:
2020-09-22



