Coagulation factor XI protease domain in complex with active site inhibitor
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6ts6
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资源简介：
Coagulation factor XI protease domain in complex with active site inhibitor Descriptor: 2-[2-[[3-[(3~{S})-3-azanyl-2,3-dihydro-1-benzofuran-5-yl]-5-(2-cyanopropan-2-yl)phenyl]methoxy]phenyl]ethanoic acid, Coagulation factor XI, DIMETHYL SULFOXIDE, ... Authors: Renatus, M, Schiering, N. Deposit date: 2019-12-20 Release date: 2020-07-08 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.33 Å) Cite: Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J.Med.Chem., 63, 2020
创建时间：
2019-12-20
