Structure of SARS-CoV-2 Mpro mutant (K90R) in complex with Nirmatrelvir (PF-07321332)
收藏Protein Data Bank Japan2024-10-23 更新2026-04-04 收录
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Structure of SARS-CoV-2 Mpro mutant (K90R) in complex with Nirmatrelvir (PF-07321332) Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 Authors: Greasley, S.E, Ferre, R.A, Liu, W, Stewart, A.E. Deposit date: 2022-02-23 Release date: 2022-03-09 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.088 Å) Cite: Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants. J.Biol.Chem., 298, 2022
创建时间：
2022-02-23
