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Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors Descriptor: 1,2-ETHANEDIOL, 6-(1H-PYRAZOL-3-YL)-3-(1H-PYRAZOL-4-YL)IMIDAZO[1,2-A]PYRAZINE, SERINE/THREONINE-PROTEIN KINASE CHK1 Authors: Matthews, T.P, McHardy, T, Klair, S, Boxall, K, Fisher, M, Cherry, M, Allen, C.E, Addison, G.J, Ellard, J, Aherne, G.W, Westwood, I.M, vanMontfort, R, Garrett, M.D, Reader, J.C, Collins, I. Deposit date: 2010-05-19 Release date: 2010-07-07 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Design and Evaluation of 3,6-Di(Hetero)Aryl Imidazo[1,2-A]Pyrazines as Inhibitors of Checkpoint and Other Kinases. Bioorg.Med.Chem.Lett., 20, 2010
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2010-05-19
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