Additional file 1 of Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses

Additional file 1: Supplementary Tables. Table S1. Variant grouping strategies of 48 Interleukin-1 pathway related genes. Table S2. Molecular Inversion Probes (MIPs) covering all coding exons of 48 genes of the Interleukin-1 pathway. Table S3. Non-synonymous variant list. Table S4. Gene-level SKAT output. Table S5. Subpathway-level SKAT output. Table S6. Inflammatory-phenotype level SKAT output. Table S7. Validation SKAT output – permutations. Table S8. Synonymous variant list. Table S9. Validation SKAT output – synonymous. Table S10. Validation SKAT output – extreme outliers. Table S11. Common coding and non-coding IL38 set single SNP linear model parameters. Table S12. GWAS P-value versus SKAT adjP-value.