Expression data from stromal cells derived from idiopathic pulmonary fibrosis, lung adenocarcinoma and normal lung.

Idiopathic pulmonary fibrosis (IPF) and lung cancer share common risk factors, epigenetic and genetic alterations, cellular and molecular aberrations, the activation of similar signaling pathways and poor survival. The aim of this study was to examine the gene expression profiles of stromal cells from patients with IPF and lung adenocarcinoma (ADC) as well as from normal lung. Gene expression was evaluated in stromal cells cultured from tumor and corresponding tumor-free peripheral lung of the patients with ADC undergoing lung cancer-resection surgery (n=4), and from surgical lung biopsy samples of the patients with IPF (n=3). In addition, gene expression was evaluated in one IPF sample derived from peripheral lung outside the tumor from a patient operated for lung cancer (n=1).