WGS of 5-FC resistant mutants
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA952138
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资源简介:
2 environmental strains of S. cerevisiae were subjected to a fluctuation assay to generate hundreds of mutants resistant to the antifungal flucytosine (5-FC). We sequenced 276 mutants and 6 control strains by WGS to identify the resistance-conferring mutations and found that most harbor loss-of-function mutations in the gene FUR1, which encodes an enzyme involved in the metabolism of 5-FC
创建时间:
2023-04-04



