optofMRI_DRN

The project about optogenetic fMRI stimulating dorsal raphe serotonin neurons under awake state and anesthetized state. Findings of the works - Functional map of serotonergic activation by optogenetics, including reward-related network - General anesthetics, isoflurane, reverses brain-wide activation by DRN stimulation - Functional map was correlated with structural density. - The expression of 5-HT receptors and structural density can explain the functional maps. - General anesthetics may change receptor response. Codes are also available from github. https://github.com/Taiyou/OptofMRI_5HT/tree/main