NHLBI TOPMed: Women's Health Initiative (WHI)

This is Whole Genome Sequencing data from the TOPMed participation of the Women's Health Initiative. Approximately 11,100 subjects were involved in this study: approximately 1,100 cases of VTE, 4,000 cases of ischemic stroke, 900 cases of hemorrhagic stroke, and 5,100 controls. Summary level phenotypes for the WHI Cohort study participants can be viewed at the top-level study page phs000200 WHI Cohort. Individual level phenotype data and molecular data for all WHI top-level study and substudies are available by requesting Authorized Access to the WHI Cohort study phs000200.]]>
TOPMed Whole Genome Sequencing Methods: Freeze 9TOPMed Whole Genome Sequencing Methods: Freeze 10The study population consists of approximately 11,100 women who were enrolled in the WHI Clinical Trials and Observational Studies between 1992 and 1998. The inclusion criteria for cases were consent status allowing for data sharing through dbGaP, and incidence case of stroke or venous thromboembolism after enrollment in WHI. Inclusion criteria for controls were consent status allowing for data sharing through dbGaP, and no history of stroke or VTE.]]>
Please see the WHI Top Level study phs000200 for a study history of the WHI study.]]>