Discovery of a high affinity inhibitor of cGAS
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Discovery of a high affinity inhibitor of cGAS Descriptor: (1R,2S)-2-[(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid, CYCLIC GMP-AMP SYNTHASE, ZINC ION Authors: Hall, J. Deposit date: 2018-12-06 Release date: 2018-12-19 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.23 Å) Cite: Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay. PLoS ONE, 12, 2017
创建时间：
2018-12-06
