DNA damage-induced HSPC failure depends on ROS accumulation downstream of IFN-1 signaling and Bid mobilization

ChEBI2016-08-02 更新2026-07-12 收录

造血干细胞损伤机制

DNA损伤信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-85076 数据链接链接失效反馈

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资源简介：

DNA damage-induced HSPC failure depends on ROS accumulation downstream of IFN-1 signaling and Bid mobilization

创建时间：

2016-08-02

A virus-borne DNA damage signaling pathway controls the lysogeny-induction switch of a group of temperate pleolipoviruses. A virus-borne DNA damage signaling pathway controls the lysogeny-induction switch of a group of temperate pleolipoviruses

溶原调控

DNA损伤信号通路

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DNA damage-induced HSPC failure depends on ROS accumulation downstream of IFN-1 signaling and Bid mobilization

造血干细胞损伤机制

DNA损伤与氧化应激

Targeted mouse mutants with inactivated Mixed-Lineage-Leukemia-5 (Mll5, MGI:1924825) alleles exhibit numerical, cell cycle and functional abnormalities in their hematopoietic stem and progenitor cell

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APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression

肿瘤基因组突变机制

DNA损伤信号通路

Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) DNA cytosine deaminase 3B (A3B) is a DNA editing enzyme which induces genomic DNA mutations in multiple myeloma and in various

Figshare2020-01-08 更新50

DNA damage signaling gene array on SMA mouse skeletal muscle

脊髓性肌萎缩症分子机制

DNA损伤信号通路

A commercially available gene array (SABiosciences array PAMM-029ZD-12) was used to assay gene expression in skeletal muscle of SMA mice and control littermates. The Taiwanese severe SMA mouse model w

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Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection. Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection

造血干细胞损伤机制

疟疾感染微环境调控

Severe infections are a major stress on haematopoiesis, where the consequences for haematopoietic stem cells (HSCs) have only recently started to emerge. HSC function critically depends on the integri

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DNA damage-induced HSPC failure depends on ROS accumulation downstream of IFN-1 signaling and Bid mobilization

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