Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems
收藏官方服务：
资源简介：
Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems
应用场景：
创建时间：
2014-12-17
相关数据集
Shigella induces epigenetic reprogramming of zebrafish neutrophils
Trained immunity is a long-term memory of innate immune cells, generating an improved response upon re-infection. Shigella is an important human pathogen and inflammatory paradigm for which there is n
NIAID Data Ecosystem90
Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote
The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embryogenesis to establish full developmental potential.
NIAID Data Ecosystem50
HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]. HIF-1 directly induces TET3 expression to redistribute 5-hydroxymethylcytosine and induce erythroid gene expression in hypoxia [RNA-seq]
We performed RNA-sequencing on erythropoietic cells cultured in normoxia or hypoxia at days 3,7, and 10. We found numerous expression changes induced by hypoxia, including the canonical hypoxia target
NIAID Data Ecosystem40
Ago1 controls myogenic differentiation by regulating eRNA mediated CBP guided epigenome reprogramming
The role of Argonaute (Ago) proteins in post-transcriptional gene silencing in the cytoplasm is well characterized. However, its nuclear function still remains elusive. In this work, we investigated t
NIAID Data Ecosystem50
Selective reactivation of human X-linked genes in female fibroblasts reprogrammed by cell fusion. Selective reactivation of human X-linked genes in female fibroblasts reprogrammed by cell fusion
In female mammals, one of the two X chromosomes is silenced as pluripotent cells differentiate. This process, termed X-inactivation, is random and results in mosaic expression of many X-linked genes i
NIAID Data Ecosystem40
