Data Collection, Phasing and Refinement Statistics.

aValues in parentheses are for the highest-resolution shell.bRsym = ∑h∑i |(Ii(h)-|/∑h∑I Ii(h), where Ii(h) is the I-th measurement of reflection h, and is the weighted mean of all measurements of h.cFigure Of Merit before Density Modification.dRwork = ∑|Fobs-Fcalc|/∑Fobs where Fobs = observed structure factor amplitude and Fcalc = structure factor calculated from model. Rfree is computed in the same as Rwork, but using the test set of reflections.