FoxA1 is a critical determinant of Estrogen Receptor function and endocrine response
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FoxA1 is a critical determinant of Estrogen Receptor function and endocrine response
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创建时间：
2010-11-17
相关数据集
Aorta- and liver-specific ERalpha-binding patterns and gene regulation by estrogen (ChIP-seq)
Estrogen has vascular protective effects in premenopausal women and in women under 60 receiving hormone replacement therapy. However, estrogen also increases risks of breast and uterine cancers and of
NIAID Data Ecosystem100
Temporal transcriptional response from primary human chronic lymphocytic leukemia (CLL)-cells after B-cell receptor stimulation.
The B-cell receptor (BCR) signaling is crucial for the pathophysiology of most leukemias and lymphomas originated from mature B lymphocytes and has emerged as a new therapeutic target, especially for
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GO:0004879 (nuclear receptor activity)
This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.
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Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER. Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER
We used the endometrial adenocarcinoma cell line in which the ERα cDNA gene was transfected and forcedly expressed ER. Then the factors induced by estrogen (Estradiol: E2) were measured by microarray.
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Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.
Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript
NIAID Data Ecosystem40
