官方服务：
资源简介：
Mapping the Molecular Pheno-Conversion from Normal Coronary Artery to Advanced Atherosclerotic Plaque
应用场景：
创建时间：
2025-10-01
相关数据集
Circulating Mononuclear Cell Transcriptomes in Patients with Atherosclerotic Coronary Artery Disease. Homo sapiens
Monocytes and T-cells play an important role in the development of atherosclerotic coronary artery disease (CAD). Differences in transcriptional activity of these cells might reflect the individual's
NIAID Data Ecosystem50
RNA-seq of stable and unstable section of human atherosclerotic plaques
Atherosclerosis is a serious and very common condition where plaque builds up inside arteries and that can lead to heart attack or stroke. The development and rupture of the plaque is a complex proces
NIAID Data Ecosystem30
Transcriptional study of oxLDL-induced foam cell formation in WT and Atf3-/- murine bone marrow macrophages
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipid-loaded macrophages in the arterial wall. Intimal macrophages internalize modified lipoproteins such as oxid
NIAID Data Ecosystem10
Single Cell RNA Seq Reveals a Distinct Immune Landscape in Vulnerable Coronary Plaques.
We observed a unique compositional difference between the stable and vulnerable plaques. Neutrophils, mast cells, and IL1B inflammatory macrophages were detected only in vulnerable plaques. Overall de
NIAID Data Ecosystem40
Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci (ChIP-Seq). Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci (ChIP-Seq)
To better understand the fundamental molecular mechanisms that contribute to complex human diseases such as coronary artery disease (CAD), we have created a catalog of genetic variants associated with
NIAID Data Ecosystem20
