Oxovanadium(V) and Dioxomolybdenum(VI) Complexes of Amide–Imine Conjugates: Structures, Catalytic and Antitumor Activities

Three
new amide–imine conjugates, namely [(E)-2-hydroxy-N′-((2-hydroxynaphthalen-1-yl)­methylene)­benzohydrazide]
(SALNP), [(E)-N′-(4-(diethylamino)-2-hydroxybenzylidene)-2-hydroxybenzohydrazide]
(SALSD), and [(E)-N′-(3-ethoxy-4-hydroxybenzylidene)-2-hydroxybenzohydrazide]
(SALVN), derived by reacting 2-hydroxybenzohydrazide (SAL) with three
different aldehyde, 2-hydroxynapthaldehyde, 4-(diethylamino)-2-hydroxybenzaldehyde,
and 3-ethoxy-4-hydroxybenzaldehyde, respectively. Three mononuclear
oxovanadium­(V) and two μoxo-bridged dinuclear molybdenum­(VI)
complexes have been synthesized using SALNP and SALSD. Besides, SALVN
is used to prepare oxovanadium­(V) and dioxomolybdenum­(VI) complexes.
All five metal complexes along with three amide–imine conjugates
are characterized by single crystal XRD analysis. Some of them have
been explored as catalyst for oxidation of alkyl benzene and styrene.
Antitumor activities of the metal complexes along with ligands have
been studied on Dalton lymphoma (DL) and 2PK3 murine lymphoma cells.