Modulation of host gene expression by Hepatitis E virus ORF3 protein. Homo sapiens

Analysis of human liver cell line (Huh7) infected with HEV ORF3 expressing (Ad-orf3-egfp) and control recombinant adenovirus (Ad-egfp). Hepatitis E virus ORF3 protein (pORF3) is known to modulate the host cell. Results provide insight into the role of this protein for HEV infection and pathogenesis. Overall design: The gene expression experiment of Huh7 hepatoma cell line infected with ORF3 expressing recombinant adenoviruses (Ad-orf3-egfp) and with control recombinant adenoviruses (Ad-egfp) was performed in replicates of three.