List of sites found to be under pervasive negative selection by FEL (p≤0.05) along internal branches in BA.5.

Coordinate (SARS-CoV-2): the starting coordinate of the codon in the NCBI reference SARS-CoV-2 genome. Gene/ORF: which gene or ORF does this site belong to. Codon (in gene/ORF): the location of the codon in the corresponding Gene/ORF. Synonymous rate: Site estimate for the synonymous substitution rate (alpha). These values are highly imprecise and should be viewed as qualitative measures. Non-synonymous rate: Site estimate for the non-synonymous substitution rate (beta). These values are highly imprecise and should be viewed as qualitative measures. p-value: the p-value for the likelihood ratio test. “q-value”: multiple-test corrected q-value (Benjamini-Hochberg). (CSV)