Additional file 2 of Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features

Additional file 2: Table S1. Patient and clinico-pathological characteristics of the cohort used for creating patient-derived scaffold cultures with MCF7 or MDA-MB-231. Table S2. Primer list. Table S3. P-values of the Pearson correlation analyses between the drug fingerprints for each gene in the individual MCF7 PDSs treated with 5-FU and plotted Fig. 3C. Table S4. P-values of the Pearson correlation analyses between the drug fingerprints for each gene in the individual MCF7 PDSs treated with DOX and plotted in Fig. 3D. Table S5. P-values of the Pearson correlation analyses between the drug fingerprints for each gene in the individual MCF7 PDSs 5-FU versus DOX and plotted in Fig. 3E. Table S6. Median values and P-values of Mann–Whitney U comparison between gene expression in MCF7 patient-derived scaffolds and clinical parameters. Table S7. Univariate and multivariable cox-regression analyses of gene expression data from MCF7 cells grown in the patient-derived scaffolds following treatment with 5-fluorouracil or doxorubicin. Table S8. Log-rank tests of the Kaplan–Meier plots illustrating disease free survival in patient-derived scaffolds cultured with MCF7 and treated with 5-fluorouracil and doxorubicin. Table S9. P-values the Pearson correlation analyses between the drug fingerprints for each gene in the individual MDA-MB-231 PDSs 5-FU versus DOX and plotted in Fig. 5B. Table S10. P-values of the Pearson correlation analyses between the MCF7 and MDA-MB-231 drug fingerprints for each gene in the individual PDSs treated with 5-FU (top) or DOX (bottom) and plotted in Fig. S6C. Table S11. Median values and P-values of Mann–Whitney U comparison between gene expression in MDA-MB-231 patient-derived scaffolds and clinical parameters. Table S12. Univariate and multivariable cox-regression analyses in patient-derived scaffolds cultured with MDA-MB-231 following treatment with 5-fluorouracil and doxorubicin. Table S13. Table with P-values from log-rank tests of the Kaplan Meier plots illustrating disease-free survival in patient-derived scaffolds cultured with MDA-MB-231 and treated with 5-fluorouracil and doxorubicin.