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Human octameric PAICS in complex with SAICAR, AMP-PNP, and magnesium

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6yb9
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Human octameric PAICS in complex with SAICAR, AMP-PNP, and magnesium Descriptor: (2~{S})-2-[[5-azanyl-1-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]imidazol-4-yl]car bonylamino]butanedioic acid, 1,2-ETHANEDIOL, MAGNESIUM ION, ... Authors: Skerlova, J, Unterlass, J, Gottmann, M, Homan, E, Helleday, T, Jemth, A.S, Stenmark, P. Deposit date: 2020-03-16 Release date: 2020-07-08 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.406 Å) Cite: Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target. J.Biol.Chem., 295, 2020
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2020-03-16
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