Raw Xenium Prime 5K and Chromium Flex output for: "Spatial Transcriptomics Identifies Immune-Stromal Niches Associated with Cancer in Adult Dermatomyositis"

This dataset contains the raw output files from spatial transcriptomics and single-cell RNA sequencing of skin biopsies from adult patients with dermatomyositis (DM), cutaneous lupus erythematosus (CLE), and healthy controls, supporting our study "Spatial Transcriptomics Identifies Immune-Stromal Niches Associated with Cancer in Adult Dermatomyositis". Data are provided in two compressed archives. Each sample is stored in its own subfolder. Each per-sample folder contains the standard Xenium output. raw_spatial_output.zip — Xenium Prime 5K (10x Genomics) Raw output from the Xenium Analyzer for 19 skin biopsies: 12 DM lesional samples, 4 CLE lesional samples, 3 healthy control samples raw_flex.zip — Chromium Single Cell Gene Expression Flex (10x Genomics) Filtered feature-barcode matrices from cellranger for 44 skin biopsies: 22 DM lesional samples, 9 CLE lesional samples, 8 non-lesional samples from a subset of patients, 6 healthy controls Each per-sample folder contains the standard 10x Matrix output (sample_filtered_feature_bc_matrix/): barcodes.tsv.gz — cell barcodes features.tsv.gz — gene IDs and symbols matrix.mtx.gz — sparse cell × gene count matrix