Abstract: Nonoptimal synonymous codon usage represses gene expression, but the underlying mechanisms are poorly understood. We and others have shown that nonoptimal codons slow translation elongation
The RSCU values of each sequence and the first 2 PCA factors. This file contains all the calculated RSCU values of each sequence and the first 2 PCA factors. The stop codons were not included and thus
Relative synonymous codon usage was calculated for all genomes in the Y1000+ database. The RSCU for orders with a CTG codon reassignment were computed taking the reassignment into account. The script
Since its elucidation, the codon table has played a pivotal role in aiding our understanding of how cells read the sequence in DNA and translate it into a protein sequence. But, at a fundamental level