Synthesis and Resolution of Substituted [5]Carbohelicenes
收藏NIAID Data Ecosystem2026-03-08 收录
下载链接：
https://figshare.com/articles/dataset/Synthesis_and_Resolution_of_Substituted_5_Carbohelicenes/2156680
下载链接
链接失效反馈官方服务：
资源简介：
Three types of racemic [5]helicenyl
acetates (1a, 2, and 3a) were
synthesized. The synthesis of 2 was achieved by regioselective
oxidation using o-iodoxybenzoic acid. The enzymatic
kinetic resolution of 1a–3a was studied.
The conversion with the highest
rate and ee was obtained using 1a as
the substrate and lipase Amano PS-IM as the enzyme. The two enantiomers
of 1-[5]helicenol 3b were separated using (1S)-10-camphorsulfonyl chloride as the chiral resolving agent.
创建时间：
2016-02-13
