Gene Expression profiles of normal and tumor colon tissues from CDX2; Dmt1+/+/ApcF/+, CDX2; Dmt1F/F/ApcF/+. Mus musculus

To investigate the detailed molecular mechanisms for the regulatory role of Dmt1 in colon tumorigenesis, microarray gene expression analysis was performed on normal and tumor colon tissue RNA isolated from 3-month-old CDX2; Dmt1+/+/ApcF/+and CDX2; Dmt1F/F/ApcF/+ mice. Overall design: Global gene expression profiling in colon tissue RNAs isolated from 3-month-old CDX2; Dmt1+/+/ApcF/+ (n=7; shah038, normal; shah040, tumor) and CDX2; Dmt1F/F/ApcF/+ (n=4; shah039, normal; shah041, tumor).