Single cell RNA sequencing of medial and lateral hippocampal network neurons in the mouse
收藏Alliance of Genome Resources2026-08-01 收录
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By comparing single cell transcriptomes of neurons participating in medial vs. lateral hippocampal networks in the mouse, we identify Latrophilin-2 as a molecular marker of the lateral network. We dissected vGlut1Cre+ neurons from P8 mice from 6 subregions: proximal CA1, distal CA1, medial entorhinal cortex, lateral entorhinal cortex, proximal subiculum, and distal subiculum, dissociated the tissue with papain, and performed plate-based SmartSeq2-based single cell RNA sequencing.
