VEGFR3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection

To investigate the transcriptomic characteristics of CD11b+F4/80+ cells in the brain of JEV- infected WT and Vegfr-3?LBD/?LBD mice, we sorted the CD11b+F4/80+ cells from the brain of WT and Vegfr-3?LBD/?LBD mice post 5 days of JEV infection by FACS. We then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells. Overall design: Comparative gene expression profiling analysis of RNA-seq data for CD11b+F4/80+ cells in the brain of JEV- infected WT and Vegfr-3?LBD/?LBD mice.