A,B. Body weights of the 1-wk study (Fig. 3A-D). C. Body weights for the 4-week and 8-week study (Fig. 3E-L). D. Liver gene expression of 1-wk treatment with PF-04991532. E-G. Plasma insulin of drug t
Results from every deletion experiment in the article as well as the assignment of gene essentiality for optimal growth from the 6 cell-lines of the two studies used in the validation of the network.
These data are the primary data of the paper "A High-Fat Diet Reverses Metabolic Disorders and Premature Aging by Modulating Insulin and IGF1 Signaling in SIRT6 Knockout Mice"