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Transcription profiling of mouse stratified epithelial spontaneous SCC induced by the somatic inactivation of Rb1 and Trp53 tumor suppressors

ChEBI2008-06-16 更新2026-07-21 收录

鳞状细胞癌分子机制

肿瘤抑制基因

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-9144 数据链接链接失效反馈

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资源简介：

Transcription profiling of mouse stratified epithelial spontaneous SCC induced by the somatic inactivation of Rb1 and Trp53 tumor suppressors

应用场景：

创建时间：

2008-06-16

鳞状细胞癌分子机制

Ras/ERK信号通路调控

Nuclear import, mediated in part by karyopherin-alpha 4 (KPNA) subtypes, regulates transcription factor access to the genome and determines cell fate. However, the cancer-specific changes of KPNA subt

NIAID Data Ecosystem60

Transcription profiling of transfected A549 lung cancer cell line with new tumor supressor gen ARLTS1 in that shows a very low expression level in comparison with normal lung

肿瘤抑制基因

癌细胞转录组

We have transfected a new tumor suppresor gene named ARLTS1 in A549 lung cancer cell line that shows a very low expression level in comparison with normal lung. This line was transfected using the pMV

NIAID Data Ecosystem50

The effect on gene expression of Smchd1 deletion in premalignant pre-B cells

B细胞淋巴瘤分子机制

肿瘤抑制基因

Smchd1 appears to act as a tumour suppressor in the Eµ-Myc B cell lymphoma model. We find gene expression differences are most pronounced in premalignant cells. We always detect a small number of clus

NIAID Data Ecosystem40

TAp63-regulated microRNAs suppress cutaneous squamous cell carcinoma [RNA-seq]

鳞状细胞癌分子机制

microRNA治疗

The goal of this study is to compare the differences in the global mRNA expression of WT and TAp63-/- skin and SCC TAp63 is a p53 family member and potent tumor and metastasis suppressor. Here, we sho

NIAID Data Ecosystem60

Broad H3K4me3 Reveals Increased Transcription Elongation and Enhancer Activity at Tumor Suppressors. Homo sapiens

肿瘤表观遗传学

肿瘤抑制基因

Tumor suppressors are mostly defined by inactivating somatic mutations in tumors, yet little is known about their epigenetic features in normal cells. Here, through integrative analysis of 1,134 genom

NIAID Data Ecosystem40

Transcription profiling of mouse stratified epithelial spontaneous SCC induced by the somatic inactivation of Rb1 and Trp53 tumor suppressors

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