A systematic survey of PRMT interactomes reveals key roles of arginine methylation in the global control of RNA splicing and translation [Poly-Seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP268628
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To examine how PRMT inhibitions affect the translation of different mRNAs, we sequenced the mRNA population associated with different ribosomal fractions after treatment of PRMT1 and PRMT4 inhibitors Overall design: DMSO or Inhibitor-treated HEK293T cells were subjected to polysome profiling. Different polysome profiling fractions bound with indicated ribosomes were analyzed with RNA-seq to test translation alteration under PRMT inhibition.
创建时间：
2022-08-05
