Crystal structure of human Brachyury G177D variant in complex with SJF-4601

Crystal structure of human Brachyury G177D variant in complex with SJF-4601 Descriptor: N-(3-chloro-4-fluorophenyl)-3-[4-(dimethylamino)butanamido]-4-methoxybenzamide, T-box transcription factor T Authors: Bebenek, A, Linhares, B, Jaime-Figueroa, S, Butrin, A, Crews, C. Deposit date: 2022-12-24 Release date: 2024-02-28 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.03 Å) Cite: Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury. Angew.Chem.Int.Ed.Engl., 63, 2024