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Structure of DDB1 bound to DS24-engaged CDK12-cyclin K

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Protein Data Bank Japan2024-11-13 更新2026-05-23 收录
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Structure of DDB1 bound to DS24-engaged CDK12-cyclin K Descriptor: (2~{R})-2-[[6-[(3-fluoranyl-4-pyridin-2-yl-phenyl)methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... Authors: Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. Deposit date: 2022-11-30 Release date: 2023-09-13 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.58 Å) Cite: Design principles for cyclin K molecular glue degraders. Nat.Chem.Biol., 20, 2024

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2022-11-30
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