Evaluation of the effect of morphine and maternal immune activation on pigs

Female and male pigs were studied. Half of the pigs were exposed to immune activation from virally-infected mothers, and half were not exposed. At 17 days of age half the pigs were injected with morphine for 4 days and the remainder with saline. Overall design: RNA samples were obtained at 21 days of age. The prefrontal cortex samples were subjected to paired-end RNA sequencing.