Impact of Flavonoid compounds on cGAS STING pathway

My PhD research is about testing some naturally occurring food components and their derivatives on different cell lines to identify their anti-inflammatory properties. Some inflammatory reactions are driven by an important regulator, which acts like a switch to turn on the inflammatory responses and can become a negative and self-destructive force when the immune system gets awry, leading to a full-blown diseases. We discovered that these compounds can dampen the signaling mediated by this regulator. This opens new therapeutic opportunities to treat several auto-immune diseases and hyperinflammatory diseases such as COVID-19.