Wild-type EGFR in covalent complex with Poziotinib analogue

Wild-type EGFR in covalent complex with Poziotinib analogue Descriptor: 1-[(3~{S})-3-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-methoxy-quinazolin-6-yl]oxypyrrolidin-1-yl]propan-1-one, Epidermal growth factor receptor Authors: Anthony, N, Pintar, S, Noble, M.E.N, Martin, M.P. Deposit date: 2024-07-05 Release date: 2025-07-16 Last modified: 2026-01-28 Method: X-RAY DIFFRACTION (1.991 Å) Cite: Factors affecting irreversible inhibition of EGFR and influence of chirality on covalent binding. Commun Chem, 8, 2025